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On the medicinal chemistry of ferrocene

Identifieur interne : 001B22 ( Main/Exploration ); précédent : 001B21; suivant : 001B23

On the medicinal chemistry of ferrocene

Auteurs : Mohammad F. R. Fouda [Égypte] ; Mokhles M. Abd-Elzaher [Égypte] ; Rafeek A. Abdelsamaia [Égypte] ; Ammar A. Labib [Égypte]

Source :

RBID : ISTEX:BB8F889A306378A472CEC2729866C81C1B141542

English descriptors

Abstract

Organometallic chemistry and biochemistry have been merged in the last two decades into a new field: bioorganometallic chemistry. This new research area was devoted to the synthesis of new organometallic compounds and their biological and medical effects against some types of diseases, such as cancer and malaria. For several years, the use of ferrocene in bioorganometallic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable, nontoxic compound and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications. Copyright © 2007 John Wiley & Sons, Ltd.
The use of ferrocene in bioorganometal‐lic chemistry has been growing rapidly, and several promising applications have been developed since ferrocene is a stable compound, nontoxic and has good redox properties. This review will focus on ferrocenyl compounds which have been biologically evaluated against certain diseases. This area has attracted many researchers due to the promising results of some ferrocene compounds in the medicinal applications.

Url:
DOI: 10.1002/aoc.1202


Affiliations:


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<term>Antiproliferative effect</term>
<term>Antitumor</term>
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<term>Breast cancer cells</term>
<term>Brocard</term>
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<term>Copyright</term>
<term>Cytotoxic</term>
<term>Cytotoxic effect</term>
<term>Derivative</term>
<term>Dyson</term>
<term>Electrochemical</term>
<term>Falciparum</term>
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<term>Organometal</term>
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<term>Plasmodium falciparum</term>
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<term>Receptor</term>
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